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課程名稱 |
生物資訊學
BIOINFORMATICS |
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開課學期 |
97-1 |
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授課對象 |
學程 生物統計學程 |
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授課教師 |
林恩仲 |
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課號 |
AniSci7025 |
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課程識別碼 |
626 M1610 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三6,7,8(13:20~16:20) |
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上課地點 |
加工105室 |
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備註 |
總人數上限：15人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
This course is designed to guide graduate students applying different bioinformatic tools to launch genomic study. With real-world data and abundant information from public databases, those students will learn how to integrate and interpret gene expression and related function in gene level as well as in genomic level. |
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課程目標 |
Build up the understanding of applying bioinformatics ideas in biological research |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
Mount, D. W. 2004. Bioinformatics: Sequence and Genome Analysis. 2nd Ed. Published by: Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, U.S.A.
Baxevanis, A. D. and Francis Ouellette, B. F. (ed.) 2005. Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. 3rd Ed. Published by: John Wiley & Son, Inc., NY, U.S.A.
Gibson, G and S. V. Muse. 2004. A Primer of Genome Sciences. 2nd Ed. Published by: Sinauer Associates, Sunderland, MA, USA. |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
作業、課堂Q/A |
20% |
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2. |
Mini-project 1 |
15% |
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3. |
Mini-project 2 |
15% |
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4. |
Midterm exam |
25% |
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5. |
Final exam |
25% |
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週次 |
日期 |
單元主題 |
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第1週 |
9/17 |
History and Definition of Bioinformatics |
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第2週 |
9/24 |
Alignment of Pairs of Sequences (Global vs. Local) |
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第3週 |
10/01 |
Multiple Sequence Alignment |
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第4週 |
10/08 |
BLAST against Public Databases |
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第5週 |
10/15 |
Introduction to Public Databases (I) |
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第6週 |
10/22 |
Introduction to Public Databases (II) |
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第7週 |
10/29 |
Introduction to Public Databases (III) |
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第8週 |
11/05 |
Integration of data/information from experiments/databases |
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第9週 |
11/12 |
期中考 Midterm exam |
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第10週 |
11/19 |
Gene Prediction: Methods and Evaluation |
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第11週 |
11/26 |
SNP Prediction and Validation |
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第12週 |
12/03 |
Protein function related issues |
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第13週 |
12/10 |
Protein structure related issues |
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第14週 |
12/17 |
Data Analysis for Gene Expression (I) |
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第15週 |
12/24 |
Data Analysis for Gene Expression (II) |
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第16週 |
12/31 |
Phylogenetic Analysis |
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第17週 |
1/07 |
Summary and Conclusions |
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第18週 |
1/14 |
期末考 Final exam |
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